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Okoko, Tebekeme

tebebuddy@gmail.com

Areas of Research Interest & Specialty

S/N Research Area
1 Medicinal plant research, mechanisms of oxidative stress and antioxidation using in vitro models, response of isolated cells/tissues to environmental toxic chemicals, natural product chemistry, molecular aspects of drug interaction, bioinformatics.

School Attended with Qualifications

  • Rivers State University of Science and Technology, Port Harcourt - BSc - 2000
  • University of Northumbria at Newcastle - MSc - 2005
  • University of Northumbria at Newcastle - PhD - 2014

Membership of Professional Bodies- Year

  • Chemical Society of Nigeria - 2006
  • Institute of Chartered Chemists of Nigeria - 2007
  • Biotechnology Society of Nigeria - 2008
  • Nigerian Society for Experimental Biology - 2016
  • Nigerian Society of Biochemistry and Molecular Biology - 2017

Work Experience (Academic)
  • NYSC-Graduate Assistant, Ondo State University (Now Adekunle Ajasen University), Akungba-Akoko, Ondo State - 2000-2001
  • Graduate Assistant, Niger Delta University - 2002-2005
  • Assistant Lecturer, Niger Delta University - 2005-2007
  • Lecturer II, Niger Delta University - 2007-2010
  • Lecturer I, Niger Delta University - 2010-2015
  • Senior Lecturer, Niger Delta University - 2015-2018
  • Associate Professor, Niger Delta University - 2018-2021
  • Professor, Niger Delta University - 2021-present

Work Experience (Administrative)

Workshops and Conferences Attended

  • The 29th Annual International Conference of the Chemical Society of Nigeria held at the Airport Hotel, Ikeja, Lagos - 2006
  • The 6th Annual Conference of the Botanical Society of Nigeria held at University of Benin, Benin. - 2007
  • The 30th Annual International Conference of the Chemical Society of Nigeria held at Merit House, Abuja - 2007
  • The 21st Annual Conference of the Biotechnology Society of Nigeria held at University of Agriculture, Abeokuta - 2008
  • The 45th Annual Conference of the Science Association of Nigeria; held at Niger Delta University, Wilberforce Island - 2010
  • The 2nd Annual Zonal (South-South Zone) Conference of the Nigerian Society of Biochemistry and Molecular Biology held at University of Calabar, Calabar - 2017
  • The 36th Annual Conference of the Nigerian Society of Biochemistry and Molecular Biology held at University of Uyo, Uyo - 2017
  • The 3rd Annual Zonal (South-South Zone) Conference of the Nigerian Society of Biochemistry and Molecular Biology held at University of Port Harcourt, Port Harcourt - 2018
  • The 5th Annual Zonal (South-South Zone) Conference of the Nigerian Society of Biochemistry and Molecular Biology held at Federal University, Otuoke, Bayelsa State - 2021
  • The 38th Annual Conference of the Nigerian Society of Biochemistry and Molecular Biology held at Usmanu Danfodiyo University, Sokoto - 2021
  • Two-day training workshop on ‘Principles of Chemicals Management and Environmental Impact Assessment’ Organized by the Institute of Chartered Chemists of Nigeria held at Airport Hotel, Lagos - 2008
  • One-day training workshop on ‘Cybersecurity’ organised by the National Information Technology Development Agency (NITDA) held at Ebi’s Hotel, Yenagoa - 2018
  • Workshop entitled ‘Hidden Hunger: The role of the Academia and Policy Makers’ organized by the Nutritional Society of Nigeria held at Niger Delta University - 2019
  • Webinar entitled ‘Shedding New Light on GPCR Drug Discovery With A Novel Biosensor Technology’ organized by GEN (Genetic Engineering and Biotechnology News) - 2020
  • Webinar entitled ‘Endocrinology and Diabetes’, organized by BIOEVENTS (Medical Expo) - 2021
  • Webinar entitled ‘Creating the Future of Cell and Gene Therapies’ organized by GEN (Genetic Engineering and Biotechnology News) - 2021
  • Webinar entitled ‘Precision Genome Editing without Double-Strand Breaks’ organized by GEN (Genetic Engineering and Biotechnology News) - 2021
  • The 6th Annual Zonal (South-South) Conference of the Nigerian Society of Biochemistry and Molecular Biology held at the Federal Medical Center, Yenagoa, Bayelsa State - 2022

Articles

  		•  Okoko, T. and Ndoni, S. A. (2022). Protective role of glycine and kolaviron on lipopolysaccharide-induced alterations of raw U937 cells and U937-derived macrophages.. Notulae Scientia Biologicae, 14(1) 11082
  		• Okoko, T. and Robert, F. O. (2022). Inhibitory potential of rutin on lipopolysaccharide-induced toxicity and inflammatory response of raw U937 cells and macrophages. Notulae Scientia Biologicae, 14(3) 11294
  		• Okoko, T. and Silas-Olu, D. I (2021). In-vitro anti-lipid peroxidation and other antioxidant potentials of Gongronema latifolium leaf extract. Asian Journal of Research in Biochemistry. Asian Journal of Biochemistry Research, 8(1) 35-41
  		• Okoko, T and Ndoni, S. A (2021). Protective effect of kolaviron on bromate-induced toxicity on raw U937 cells and macrophages.. Malaysian Journal of Biochemistry and Molecular Biology, 2021(1) 169-17
  		• Okoko, T (2020). Glycine and selenium (separately and in combination) reduced bromate-mediated oxidative stress and inflammatory response in U937 cells. Asian Journal of Biochemistry, Genetics and Molecular Biology, 6(1) 8-16
  		• Okoko, T (2020). Assessment of the inherent in-vitro antioxidant potential of Commelina benghalensis leaf extract. Asian Journal of Biochemistry, Genetics and Molecular Biology, 6(4) 25-32
  		• Okoko, T. (2020). Bromate causes significant cytotoxicity and modulation of the inflammatory response.. Asian Journal of Biotechnology and Genetic Engineering, 3(4) AJBGE.61918
  		• Nwachukwu, A., Iyagbo, C, Onyen, J., Okoko, T. (2018). Antioxidant evaluation and inhibitory activity of Chromolaena odorata leaf extract on hydrogen peroxide-induced erythrocyte hemolysis.. American Journal of Research in Medical Sciences, 2(1) 17-23
  		• Okoko, T (2018). Paracetamol and Hydrogen peroxide-induced tissue alterations are reduced by Costus afer extract. American Journal of Research in Medical Sciences 2(2): 66-72.. American Journal of Research in Medical Sciences, 2(2) 66-72
  		• Akuru, U. B. and Okoko, T. (2018). Antihypertriglyceridemic properties of Sorghum vulgare leaf sheath on haematological indices and liver function markers on high fat diet dyslipidemic wistar-albino rats. European Journal of Biomedical and Pharmaceutical Sciences, 5(2) 440-444
  		• Okoko, T. (2018). Kolaviron and Selenium reduce hydrogen peroxide-induced alterations of the inflammatory response. Journal of Genetic Engineering and Biotechnology, 16(2) 485-490
  		• Okoko, T and Ndoni, S. A (2018). Kolaviron protects against cisplatin-induced hepatic and renal oxidative damage in rats. Oxidants and Antioxidants in Medical Science , 2(34) 34-41
  		• Ndoni, S. A., Ere, D. and Okoko, T. (2017). Assessment of the in vitro antilipid peroxidative activity of Costus afer stem extract. Oxidants and Antioxidants in Medical Science, 6(2) 30-34
  		• Gbenenee T.J., Boisa, N. and Okoko, T. (2017). Phytochemical screening and evaluation of the antioxidant activity of Ficus capreifolia leaf extract via in-vitro models.. International Journal of Biochemistry Research and Review, 17(2) 1-7
  		• Oyor, N. O., Boisa, N., Akan, J. and Okoko, T. (2017). Assessment of physical properties and heavy metals in borehole water from Ogale, Eleme Local Government Area of Rivers State. International Journal of Biochemistry Research and Review, 18(3) 1-6
  		• Silas-Olu, D. I. and Okoko, T (2017). Kolaviron reduces cadmium-induced cytotoxicity and production of reactive oxygen species by suppressing inflammatory response.". Journal of Advances in Biology and Biotechnology, 14(4) 1-10
  		• Ndoni, S. A. and Okoko, T. (2017). Comparative effect of selenium and glycine on hydrogen peroxide-induced cell death and activation of macrophage U937 cells. Journal of Genetic Engineering and Biotechnology, 15(2) 521-526
  		• Gbenenee T.J., Okoko, T. and Boisa, N. (2017). Evaluation of the anti-lipid peroxidative potential of Ficus capreifolia leaf extract using in-vitro models.. Journal of Advances in Biology and Biotechnology, 16(2) 1-8
  		• Ndoni, S. A. and Okoko, T. (2016). Alterations in the levels of some serum enzymes and liver RNA in guinea pigs treated with Bonny light crude oil.". Nigerian Journal of Oil and Gas Technology, 2(2) 88-93
  		• Okoko, T., Blagova, E. V., Whittingham, J. L et al (2015). Structural characterisation of the virulence-associated protein VapG from the horse pathogen Rhodococcus equi.. Veterinary Microbiology, 179(1) 47-52
  		• Chukwurah, P. N., B. E. A., O. A. N. and Okoko, T. (2014). Protective capacity of Artemisia annua as a potent antioxidant remedy against free radical damage. 4(Suppl 1): S92-S98. Asian Pacific Journal of Tropical Biomedicine, 4(1) S92-S98
  		• Okoko, T., and Ere, D. (2013). Some bioactive potentials of two biflavanols isolated from Garcinia kola on cadmium-induced alterations of raw U937 cells and U937-derived macrophages. Asian Pacific Journal of Tropical Medicine, 6(1) 43-48
  		• Okoko, T., and Ere, D. (2012). Reduction of hydrogen peroxide-induced erythrocyte damage by Carica papaya leaf extract.. Asian Pacific Journal of Tropical Biomedicine, 2(6) 449-453
  		• Okoko, T., and Ere, D. (2012). Hibiscus sabdariffa extractivities on cadmium-mediated alterations of human U937 cell viability and activation. Asian Pacific Journal of Tropical Medicine, 5(1) 33-36
  		• Okoko, T., and Ere, D. (2012). Antioxidant activities of Solenostemon monostachyus leaf extract using in vitro models. Scientific Research and Essays, 7(6) 621-626
  		• Okoko, T., and Awhin, E. P (2010). Glycine reduces cadmium-induced alterations in the viability and activation of macrophage U937 cells. 48 (2): 536 – 538". Food and Chemical Toxicology, 48(2) 536-538
  		• Okoko, T (2010). Significance of immune complex activation of macrophages in pigeon fanciers’ lung.. International Journal of Medicine and Medical Sciences, 2(7) 226-231
  		• Okoko, T., and Ndoni, S. (2009). The effect of Garcinia kola extract on lipopolysaccharide-induced tissue damage in rats. Tropical Journal of Pharmaceutical Research, 8(1) 27-31
  		• Okoko, T., and Oruambo, I. F (2009). Inhibitory activity of quercetin and its metabolite on lipopolysaccharide-induced activation of macrophage U937 cells. Food and Chemical Toxicology, 47(4) 809-812
  		• Okoko, T (2009). In vitro antioxidant and free radical scavenging activities of Garcinia kola seeds. Food and Chemical Toxicology, 47(10) 2620-2623
  		• Okoko, T., and Oruambo, I. F (2008). The effect of Hibiscus sabdariffa calyx extract on cisplatin-induced tissue damage in rats.. Biokemistri, 20(2) 47-52
  		• Okoko, T., and Baldwin, C. I (2008). Extrinsic Allergic Alveolitis: A not-very-well known condition in Nigeria.. Port Harcourt Medical Journal, 3(1) 3-9
  		• Okoko, T., and Oruambo, I. F. (2008). Garcinia kola extract reduced lipopolysaccharide activation of macrophages using U937 cells as a model. African Journal of Biotechnology, 7(6) 792-795
  		• Okoko, T., and Oruambo, I. F (2008). The effect of Anthocleista vogelii root extract on ethanol-induced liver damage in rats. Nigerian Journal of Botany, 21(2) 298-302
  		• Okoko, T., and Oruambo, I. F (2008). Effect of cadmium on macrophage U937 cell proliferation and Activation. Nigerian Journal of Biotechnology, 19(1) 34-38
  		• Okoko, T., and Awhin E. P. (2007). Garcinia kola extract reduced cisplatin-induced kidney dysfunction in rats.. African Journal of Biochemistry Research, 1(6) 124-126